Membrane Estrogen Receptor (GPER) and Follicle-Stimulating Hormone Receptor (FSHR) Heteromeric Complexes Promote Human Ovarian Follicle Survival

Classically, follicle-stimulating hormone receptor (FSHR)-driven cAMP-mediated signaling boosts human ovarian follicle growth and oocyte maturation. However, contradicting in vitro data suggest a different view on physiological significance of FSHR-mediated cAMP signaling. We found that the G-protei...

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Veröffentlicht in:iScience
Hauptverfasser: Casarini, Livio, Lazzaretti, Clara, Paradiso, Elia, Limoncella, Silvia, Riccetti, Laura, Sperduti, Samantha, Melli, Beatrice, Marcozzi, Serena, Anzivino, Claudia, Sayers, Niamh S., Czapinski, Jakub, Brigante, Giulia, Potì, Francesco, La Marca, Antonio, De Pascali, Francesco, Reiter, Eric, Falbo, Angela, Daolio, Jessica, Villani, Maria Teresa, Lispi, Monica, Orlando, Giovanna, Klinger, Francesca G., Fanelli, Francesca, Rivero-Müller, Adolfo, Hanyaloglu, Aylin C., Simoni, Manuela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702187/
https://ncbi.nlm.nih.gov/pubmed/33299978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101812
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