Glycosylation Pattern and in vitro Bioactivity of Reference Follitropin alfa and Biosimilars

Recombinant follicle-stimulating hormone (FSH) (follitropin alfa) and biosimilar preparations are available for clinical use. They have specific FSH activity and a unique glycosylation profile dependent on source cells. The aim of the study is to compare the originator (reference) follitropin alfa (...

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Bibliografiske detaljer
Udgivet i:Front Endocrinol (Lausanne)
Main Authors: Riccetti, Laura, Sperduti, Samantha, Lazzaretti, Clara, Klett, Danièle, De Pascali, Francesco, Paradiso, Elia, Limoncella, Silvia, Potì, Francesco, Tagliavini, Simonetta, Trenti, Tommaso, Galano, Eugenio, Palmese, Angelo, Satwekar, Abhijeet, Daolio, Jessica, Nicoli, Alessia, Villani, Maria Teresa, Aguzzoli, Lorenzo, Reiter, Eric, Simoni, Manuela, Casarini, Livio
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667556/
https://ncbi.nlm.nih.gov/pubmed/31396162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00503
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