Human LH and hCG stimulate differently the early signalling pathways but result in equal testosterone synthesis in mouse Leydig cells in vitro

BACKGROUND: Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) are glycoprotein hormones regulating development and reproductive functions by acting on the same receptor (LHCGR). We compared the LH and hCG activity in gonadal cells from male mouse in vitro, i.e. primary Leydig cells, wh...

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Bibliografski detalji
Izdano u:Reprod Biol Endocrinol
Glavni autori: Riccetti, Laura, De Pascali, Francesco, Gilioli, Lisa, Potì, Francesco, Giva, Lavinia Beatrice, Marino, Marco, Tagliavini, Simonetta, Trenti, Tommaso, Fanelli, Flaminia, Mezzullo, Marco, Pagotto, Uberto, Simoni, Manuela, Casarini, Livio
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217336/
https://ncbi.nlm.nih.gov/pubmed/28056997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-016-0224-3
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