A novel danshensu derivative ameliorates experimental colitis by modulating NADPH oxidase 4‐dependent NLRP3 inflammasome activation

We have previously reported a novel compound [4‐(2‐acetoxy‐3‐((R)‐3‐(benzylthio)‐1‐methoxy‐1‐oxopropan‐2‐ylamino)‐3‐oxopropyl)‐1,2‐phenylene diacetate (DSC)], derived from danshensu, exhibits cytoprotective activities in vitro. Here, we investigated the effects and underlying mechanisms of DSC on de...

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Pubblicato in:J Cell Mol Med
Autori principali: Pan, Li‐Long, Ren, Zhengnan, Liu, Yanyan, Zhao, Yalei, Li, Hongli, Pan, Xiaohua, Fang, Xin, Liang, Wenjie, Wang, Yang, Yang, Jun, Sun, Jia
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701520/
https://ncbi.nlm.nih.gov/pubmed/32945118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15890
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