Combinatory antibiotic treatment protects against experimental acute pancreatitis by suppressing gut bacterial translocation to pancreas and inhibiting NLRP3 inflammasome pathway

Gut bacterial translocation following impaired gut barrier is a critical determinant of initiating and aggravating acute pancreatitis (AP). Antibiotic combination (ABX; vancomycin, neomycin and polymyxin b) is capable of reducing gut bacteria, but its efficacy in AP prevention and the underlying mec...

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Bibliografiske detaljer
Udgivet i:Innate Immun
Main Authors: Jia, Lingling, Chen, Hao, Yang, Jun, Fang, Xin, Niu, Wenying, Zhang, Ming, Li, Jiahong, Pan, Xiaohua, Ren, Zhengnan, Sun, Jia, Pan, Li-Long
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2019
Fag:
Special Issue Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974879/
https://ncbi.nlm.nih.gov/pubmed/31615312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425919881502
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