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Hepsin Promotes Epithelial–Mesenchymal Transition and Cell Invasion Through the miR-222/PPP2R2A/AKT Axis in Prostate Cancer

PURPOSE: To determine the role and underlying mechanism of hepsin in epithelial–mesenchymal transition (EMT) and cell invasion in prostate cancer. METHODS: The expression of hepsin in prostate cancer tissue samples and cell lines was measured by immunohistochemical staining and Western blotting. The...

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Publicat a:Onco Targets Ther
Autors principals: Li, Ruiqian, Li, Jun, Yang, Hong, Bai, Yu, Hu, Chen, Wu, Hongyi, Jiang, Haiyang, Wang, Qilin
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701367/
https://ncbi.nlm.nih.gov/pubmed/33268993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S268025
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