MiR-221/222 promote epithelial-mesenchymal transition by targeting Notch3 in breast cancer cell lines

Basal-like breast cancer (BLBC) is an aggressive subtype with a strong tendency to metastasize. Due to the lack of effective chemotherapy, BLBC has a poor prognosis compared with luminal subtype breast cancer. MicroRNA-221 and -222 (miR-221/222) are overexpressed in BLBC and associate with metastasi...

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Detalhes bibliográficos
Publicado no:NPJ Breast Cancer
Main Authors: Liang, Yuan-Ke, Lin, Hao-Yu, Dou, Xiao-Wei, Chen, Min, Wei, Xiao-Long, Zhang, Yong-Qu, Wu, Yang, Chen, Chun-Fa, Bai, Jing-Wen, Xiao, Ying-Sheng, Qi, Yu-Zhu, Kruyt, Frank A. E., Zhang, Guo-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079079/
https://ncbi.nlm.nih.gov/pubmed/30109262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-018-0073-7
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