Loss of DEK Expression Induces Alzheimer’s Disease Phenotypes in Differentiated SH-SY5Y Cells

Alzheimer’s disease (AD) is the most common cause of dementia and is characterized by the buildup of β-amyloid plaques and neurofibrillary Tau tangles. This leads to decreased synaptic efficacy, cell death, and, consequently, brain atrophy in patients. Behaviorally, this manifests as memory loss and...

Full description

Saved in:
Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Greene, Allie N., Parks, Lois G., Solomon, Matia B., Privette Vinnedge, Lisa M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701170/
https://ncbi.nlm.nih.gov/pubmed/33304240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.594319
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items