Aryl Sulfonamides Induce Degradation of Aryl Hydrocarbon Receptor Nuclear Translocator through CRL4(DCAF15) E3 Ligase

Aryl hydrocarbon receptor nuclear translocator (ARNT) plays an essential role in maintaining cellular homeostasis in response to environmental stress. Under conditions of hypoxia or xenobiotic exposure, ARNT regulates the subset of genes involved in adaptive responses, by forming heterodimers with h...

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Bibliografske podrobnosti
izdano v:Mol Cells
Main Authors: Kim, Sung Ah, Jo, Seung-Hyun, Cho, Jin Hwa, Yu, Min Yeong, Shin, Ho-Chul, Kim, Jung-Ae, Park, Sung Goo, Park, Byoung Chul, Kim, Sunhong, Kim, Jeong-Hoon
Format: Artigo
Jezik:Inglês
Izdano: Korean Society for Molecular and Cellular Biology 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700843/
https://ncbi.nlm.nih.gov/pubmed/33168788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2020.0122
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