The Small GTPase RAC1B: A Potent Negative Regulator of-and Useful Tool to Study-TGFβ Signaling

SIMPLE SUMMARY: Transforming growth factor β (TGFβ) promotes pancreatic ductal adenocarcinoma (PDAC) primarily through its non-canonical (non-Smad) signaling arms, including signaling by the small GTPase RAC1. The human RAC1 gene also encodes for another protein, designated RAC1B, but whether this i...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Ungefroren, Hendrik, Wellner, Ulrich F., Keck, Tobias, Lehnert, Hendrik, Marquardt, Jens-Uwe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700615/
https://ncbi.nlm.nih.gov/pubmed/33266416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113475
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