A Combined Systemic Strategy for Overcoming Cisplatin Resistance in Head and Neck Cancer: From Target Identification to Drug Discovery

SIMPLE SUMMARY: The efficiency of cisplatin is limited by drug resistance in head–neck cancer (HNC) patients. In this study, we established a cisplatin resistance (CR) cell model, generated CR related transcriptome profiling, and combined application of bioinformatics methodology to discover a possi...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Chen, Yin-Ju, You, Guo-Rung, Lai, Meng-Yu, Lu, Long-Sheng, Chen, Chang-Yu, Ting, Lai-Lei, Lee, Hsin-Lun, Kanno, Yuzuka, Chiou, Jeng-Fong, Cheng, Ann-Joy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700594/
https://ncbi.nlm.nih.gov/pubmed/33238517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113482
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