Self-Nanoemulsifying System Loaded with Sildenafil Citrate and Incorporated within Oral Lyophilized Flash Tablets: Preparation, Optimization, and In Vivo Evaluation

Sildenafil citrate is a drug used throughout the world primarily to treat erectile dysfunction. Several problems with the commercially available product decrease its efficacy, such as limited solubility, delayed onset of action, and low bioavailability with a large variability in the absorption prof...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Hosny, Khaled M., Alhakamy, Nabil A., Almodhwahi, Maeen A., Kurakula, Mallesh, Almehmady, Alshaimaa M., Elgebaly, Samar S.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700536/
https://ncbi.nlm.nih.gov/pubmed/33233372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12111124
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