Self-Nanoemulsifying System Loaded with Sildenafil Citrate and Incorporated within Oral Lyophilized Flash Tablets: Preparation, Optimization, and In Vivo Evaluation

Sildenafil citrate is a drug used throughout the world primarily to treat erectile dysfunction. Several problems with the commercially available product decrease its efficacy, such as limited solubility, delayed onset of action, and low bioavailability with a large variability in the absorption prof...

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Detalhes bibliográficos
Main Authors: Khaled M. Hosny, Nabil A. Alhakamy, Maeen A. Almodhwahi, Mallesh Kurakula, Alshaimaa M. Almehmady, Samar S. Elgebaly
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-11-01
Colecção:Pharmaceutics
Assuntos:
bioavailability
sildenafil citrate
erectile dysfunction
lyophilized tablets
self-nanoemulsifying lyophilized tablet
Acesso em linha:https://www.mdpi.com/1999-4923/12/11/1124
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