Quinovic Acid Impedes Cholesterol Dyshomeostasis, Oxidative Stress, and Neurodegeneration in an Amyloid-β-Induced Mouse Model

Alzheimer's disease (AD) is a progressive neurodegenerative disorder typified by several neuropathological features including amyloid-beta (Aβ) plaque and neurofibrillary tangles (NFTs). Cholesterol retention and oxidative stress (OS) are the major contributors of elevated β- and γ-secretase ac...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Saeed, Kamran, Shah, Shahid Ali, Ullah, Rahat, Alam, Sayed Ibrar, Park, Jun Sung, Saleem, Samreen, Jo, Myeung Hoon, Kim, Min Woo, Hahm, Jong Ryeal, Kim, Myeong Ok
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700034/
https://ncbi.nlm.nih.gov/pubmed/33274012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9523758
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