Metabolic Stress Alters Antioxidant Systems, Suppresses the Adiponectin Receptor 1 and Induces Alzheimer’s Like Pathology in Mice Brain

Oxidative stress and insulin resistance play major roles in numerous neurodegenerative diseases, including Alzheimer’s disease (AD). A high-fat diet induces obesity-associated oxidative stress, neuronal insulin resistance, microglial activation, and neuroinflammation, which are considered important...

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Gepubliceerd in:Cells
Hoofdauteurs: Hahm, Jong Ryeal, Jo, Myeung Hoon, Ullah, Rahat, Kim, Min Woo, Kim, Myeong Ok
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016950/
https://ncbi.nlm.nih.gov/pubmed/31963819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010249
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