Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing’s Sarcoma Tumor Growth

SIMPLE SUMMARY: The poor clinical outcomes for Osteosarcoma (OS) and Ewing’s sarcoma (ES) patients underscore the urgency of developing novel therapeutic strategies for these pathologies. In this context, the emerging role of Sonic hedgehog (SHH) signaling in cancer has been critically evaluated, fo...

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Библиографические подробности
Опубликовано в: :Cancers (Basel)
Главные авторы: Mullard, Mathilde, Cadé, Marie, Morice, Sarah, Dupuy, Maryne, Danieau, Geoffroy, Amiaud, Jérome, Renault, Sarah, Lézot, Frédéric, Brion, Régis, Thepault, Rose Anne, Ory, Benjamin, Lamoureux, François, Corre, Isabelle, Brounais-LeRoyer, Bénédicte, Rédini, Françoise, Verrecchia, Franck
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699338/
https://ncbi.nlm.nih.gov/pubmed/33228057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113438
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