Sunitinib-Containing Carborane Pharmacophore with the Ability to Inhibit Tyrosine Kinases Receptors FLT3, KIT and PDGFR-β, Exhibits Powerful In Vivo Anti-Glioblastoma Activity

SIMPLE SUMMARY: Glioblastoma is one of the most aggressive central nervous system tumors. Combinations of therapies, such as tyrosine kinase receptor inhibition and boron neutron capture therapy (BNCT), could offer greater patients benefits over single-therapies. The aim of our study was to assess t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancers (Basel)
Egile Nagusiak: Alamón, Catalina, Dávila, Belén, García, María Fernanda, Sánchez, Carina, Kovacs, Mariángeles, Trias, Emiliano, Barbeito, Luis, Gabay, Martín, Zeineh, Nidal, Gavish, Moshe, Teixidor, Francesc, Viñas, Clara, Couto, Marcos, Cerecetto, Hugo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698965/
https://ncbi.nlm.nih.gov/pubmed/33218150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113423
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