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Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A

Novel-antibiotics are urgently needed to combat an increase in morbidity and mortality due to resistant bacteria. The preclinical candidate corallopyronin A (CorA) is a potent antibiotic against Gram-positive and some Gram-negative pathogens for which a solid oral formulation was needed for further...

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發表在:Pharmaceutics
Main Authors: Krome, Anna K., Becker, Tim, Kehraus, Stefan, Schiefer, Andrea, Steinebach, Christian, Aden, Tilman, Frohberger, Stefan J., López Mármol, Álvaro, Kapote, Dnyaneshwar, Jansen, Rolf, Chaverra-Muñoz, Lillibeth, Hübner, Marc P., Pfarr, Kenneth, Hesterkamp, Thomas, Stadler, Marc, Gütschow, Michael, König, Gabriele M., Hoerauf, Achim, Wagner, Karl G.
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698778/
https://ncbi.nlm.nih.gov/pubmed/33217948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12111105
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