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Orientia tsutsugamushi Is Highly Susceptible to the RNA Polymerase Switch Region Inhibitor Corallopyronin A In Vitro and In Vivo

Scrub typhus is a potentially lethal infection caused by the obligate intracellular bacterium Orientia tsutsugamushi. Reports on the emergence of doxycycline-resistant strains highlight the urgent need to develop novel antiinfectives against scrub typhus. Corallopyronin A (CorA) is a novel α-pyrone...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Kock, Fredericke, Hauptmann, Matthias, Osterloh, Anke, Schäberle, Till F., Poppert, Sven, Frickmann, Hagen, Menzel, Klaus-Dieter, Peschel, Gundela, Pfarr, Kenneth, Schiefer, Andrea, König, Gabriele M., Hoerauf, Achim, Fleischer, Bernhard, Keller, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913972/
https://ncbi.nlm.nih.gov/pubmed/29358295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01732-17
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