A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes

In drug discovery, assays with proximal readout are of great importance to study target-specific effects of potential drug candidates. In the field of G protein-coupled receptors (GPCRs), the determination of GPCR-G protein interactions and G protein activation by means of radiolabeled GTP analogs (...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Höring, Carina, Seibel, Ulla, Tropmann, Katharina, Grätz, Lukas, Mönnich, Denise, Pitzl, Sebastian, Bernhardt, Günther, Pockes, Steffen, Strasser, Andrea
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698210/
https://ncbi.nlm.nih.gov/pubmed/33182741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228440
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars