Molecular Evolution, Neurodevelopmental Roles and Clinical Significance of HECT-Type UBE3 E3 Ubiquitin Ligases

Protein ubiquitination belongs to the best characterized pathways of protein degradation in the cell; however, our current knowledge on its physiological consequences is just the tip of an iceberg. The divergence of enzymatic executors of ubiquitination led to some 600–700 E3 ubiquitin ligases embed...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Ambrozkiewicz, Mateusz C., Cuthill, Katherine J., Harnett, Dermot, Kawabe, Hiroshi, Tarabykin, Victor
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697756/
https://ncbi.nlm.nih.gov/pubmed/33182779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112455
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