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Combination of Inhibitors of USP7 and PLK1 has a Strong Synergism against Paclitaxel Resistance

USP7 is a promising target for the development of cancer treatments because of its high expression and the critical functions of its substrates in carcinogenesis of several different carcinomas. Here, we demonstrated the effectiveness of targeting USP7 in advanced malignant cells showing high levels...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Shin, Sol-Bi, Kim, Chang-Hyeon, Jang, Hay-Ran, Yim, Hyungshin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697005/
https://ncbi.nlm.nih.gov/pubmed/33207738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228629
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