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Combination of Inhibitors of USP7 and PLK1 has a Strong Synergism against Paclitaxel Resistance

USP7 is a promising target for the development of cancer treatments because of its high expression and the critical functions of its substrates in carcinogenesis of several different carcinomas. Here, we demonstrated the effectiveness of targeting USP7 in advanced malignant cells showing high levels...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Shin, Sol-Bi, Kim, Chang-Hyeon, Jang, Hay-Ran, Yim, Hyungshin
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697005/
https://ncbi.nlm.nih.gov/pubmed/33207738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228629
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