IL-18 But Not IL-1 Signaling Is Pivotal for the Initiation of Liver Injury in Murine Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is rising in prevalence, and a better pathophysiologic understanding of the transition to its inflammatory phenotype (NASH) is key to the development of effective therapies. To evaluate the contribution of the NLRP3 inflammasome and its downstream effectors...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hohenester, Simon, Kanitz, Veronika, Schiergens, Tobias, Einer, Claudia, Nagel, Jutta, Wimmer, Ralf, Reiter, Florian P., Gerbes, Alexander L., De Toni, Enrico N., Bauer, Christian, Holdt, Lesca, Mayr, Doris, Rust, Christian, Schnurr, Max, Zischka, Hans, Geier, Andreas, Denk, Gerald
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696705/
https://ncbi.nlm.nih.gov/pubmed/33202693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228602
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