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Underestimated Peripheral Effects Following Pharmacological and Conditional Genetic Microglial Depletion

Microglia, predominant parenchymal resident macrophages in the central nervous system (CNS), are crucial players in neurodevelopment and CNS homeostasis. In disease conditions, pro-inflammatory microglia predominate over their regulatory counterparts, and are thus a potential immunotherapeutic targe...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Han, Jinming, Fan, Yueshan, Zhou, Kai, Zhu, Keying, Blomgren, Klas, Lund, Harald, Zhang, Xing-Mei, Harris, Robert A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696443/
https://ncbi.nlm.nih.gov/pubmed/33203068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228603
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