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Underestimated Peripheral Effects Following Pharmacological and Conditional Genetic Microglial Depletion

Microglia, predominant parenchymal resident macrophages in the central nervous system (CNS), are crucial players in neurodevelopment and CNS homeostasis. In disease conditions, pro-inflammatory microglia predominate over their regulatory counterparts, and are thus a potential immunotherapeutic targe...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Han, Jinming, Fan, Yueshan, Zhou, Kai, Zhu, Keying, Blomgren, Klas, Lund, Harald, Zhang, Xing-Mei, Harris, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696443/
https://ncbi.nlm.nih.gov/pubmed/33203068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228603
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