Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war

Catalysis of cis/trans isomerization of prolines is important for the activity and misfolding of intrinsically disordered proteins. Catalysis is achieved by peptidylprolyl isomerases, a superfamily of molecular chaperones. Here, we provide atomic insight into a tug-of-war between cis/trans isomeriza...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Favretto, Filippo, Flores, David, Baker, Jeremy D., Strohäker, Timo, Andreas, Loren B., Blair, Laura J., Becker, Stefan, Zweckstetter, Markus
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695863/
https://ncbi.nlm.nih.gov/pubmed/33247146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19844-0
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