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Production of lentiviral vectors in suspension cells using low proportion of supercoiled circular plasmid DNA
The supercoiled circular (SC) topology form of plasmid DNA has been regarded to be advantageous over open circular or linearized analogue in transfection and expression efficiency, and therefore are largely demanded in the biopharmaceutical manufacturing. However, production of high-purity SC plasmi...
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| Vydáno v: | Cytotechnology |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer Netherlands
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7695760/ https://ncbi.nlm.nih.gov/pubmed/33123933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-020-00433-4 |
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