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A lead candidate functional single nucleotide polymorphism within the WARS2 gene associated with waist-hip-ratio does not alter RNA stability

We have prioritised a single nucleotide polymorphism (SNP) rs2645294 as one candidate functional SNP in the TBX15-WARS2 waist-hip-ratio locus using posterior probability analysis. This SNP is located in the 3′ untranslated region of the WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial) gene with...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta Gene Regul Mech
Main Authors: Mušo, Milan, Dumbell, Rebecca, Pulit, Sara, Sinnott-Armstrong, Nasa, Laber, Samantha, Zolkiewski, Louisa, Bentley, Liz, Claussnitzer, Melina, Cox, Roger D.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695619/
https://ncbi.nlm.nih.gov/pubmed/33007465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2020.194640
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