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Andexanet versus prothrombin complex concentrates: Differences in reversal of factor Xa inhibitors in in vitro thrombin generation

BACKGROUND: Andexanet alfa (andexanet) is a modified human factor Xa (FXa) approved for anticoagulation reversal in patients with life‐threatening bleeding treated with rivaroxaban or apixaban. Four‐factor prothrombin complex concentrates (4F‐PCCs) are approved for reversal of vitamin K antagonist–i...

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Bibliografiske detaljer
Udgivet i:Res Pract Thromb Haemost
Main Authors: Lu, Genmin, Lin, Joyce, Bui, Khanh, Curnutte, John T., Conley, Pamela B.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695565/
https://ncbi.nlm.nih.gov/pubmed/33313467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12418
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