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DNA methylation-based age estimation in pediatric healthy tissues and brain tumors

Several DNA methylation clocks have been developed to reflect chronological age of human tissues, but most clocks have been trained on adult samples. The rapid methylome changes in children and the role of epigenetics in pediatric tumors calls for tools accurately estimating methylation age in child...

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Библиографические подробности
Опубликовано в: :Aging (Albany NY)
Главные авторы: Kling, Teresia, Wenger, Anna, Carén, Helena
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695434/
https://ncbi.nlm.nih.gov/pubmed/33168783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202145
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