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IGF2 loss of imprinting enhances colorectal cancer stem cells pluripotency by promoting tumor autophagy

Cancer stem cells (CSCs) are believed to be the driving force behind the tumor growth. We performed this study to further explore the role of IGF2 epigenetic on CRC stem cells pluripotency which showed that IGF2 LOI CRC cells usually had a higher CD133 expression and sphere forming efficiency than M...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Gao, Tianyi, Liu, Xiangxiang, He, Bangshun, Pan, Yuqin, Wang, Shukui
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695407/
https://ncbi.nlm.nih.gov/pubmed/33173015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103837
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