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IGF2 loss of imprinting enhances colorectal cancer stem cells pluripotency by promoting tumor autophagy

Cancer stem cells (CSCs) are believed to be the driving force behind the tumor growth. We performed this study to further explore the role of IGF2 epigenetic on CRC stem cells pluripotency which showed that IGF2 LOI CRC cells usually had a higher CD133 expression and sphere forming efficiency than M...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Gao, Tianyi, Liu, Xiangxiang, He, Bangshun, Pan, Yuqin, Wang, Shukui
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695407/
https://ncbi.nlm.nih.gov/pubmed/33173015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103837
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