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Angiotensin II-Induced Cardiovascular Fibrosis Is Attenuated by NO-Sensitive Guanylyl Cyclase1

In the NO/cGMP signaling cascade, relevant in the cardiovascular system, two NO-sensitive guanylyl cyclase (NO-GC) isoforms are responsible for NO-dependent cGMP generation. Here, the impact of the major NO-GC isoform, NO-GC1, on fibrosis development in the cardiovascular system was studied in NO-GC...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Broekmans, Kathrin, Giesen, Jan, Menges, Lukas, Koesling, Doris, Russwurm, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695185/
https://ncbi.nlm.nih.gov/pubmed/33171621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112436
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