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Targeted nanobody complex enhanced photodynamic therapy for lung cancer by overcoming tumor microenvironment
BACKGROUND: To investigate the efficacy of a PLGA-based nanobody complex in photodynamic therapy (PDT) and NIR-II imaging in A549 tumor hypoxic model. METHOD: IR1048-MZ was firstly synthesized by conjugating a nitro imidazole group to IR1048. IR1048-MZ and Cat were then encapsulated in PLGA-SH solut...
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| Gepubliceerd in: | Cancer Cell Int |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7694906/ https://ncbi.nlm.nih.gov/pubmed/33292202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01613-0 |
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