Single-cell transcriptional diversity is a hallmark of developmental potential

Single-cell RNA sequencing (scRNA-seq) is a powerful approach for reconstructing cellular differentiation trajectories. However, inferring both the state and direction of differentiation is challenging. Here, we demonstrate a simple, yet robust, determinant of developmental potential—the number of e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Science
Egile Nagusiak: Gulati, Gunsagar S., Sikandar, Shaheen S., Wesche, Daniel J., Manjunath, Anoop, Bharadwaj, Anjan, Berger, Mark J., Ilagan, Francisco, Kuo, Angera H., Hsieh, Robert W., Cai, Shang, Zabala, Maider, Scheeren, Ferenc A., Lobo, Neethan A., Qian, Dalong, Yu, Feiqiao B., Dirbas, Frederick M., Clarke, Michael F., Newman, Aaron M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694873/
https://ncbi.nlm.nih.gov/pubmed/31974247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax0249
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak