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Controlling the Switch from Neurogenesis to Pluripotency during Marmoset Monkey Somatic Cell Reprogramming with Self-Replicating mRNAs and Small Molecules

Induced pluripotent stem cells (iPSCs) hold enormous potential for the development of cell-based therapies; however, the safety and efficacy of potential iPSC-based treatments need to be verified in relevant animal disease models before their application in the clinic. Here, we report the derivation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Petkov, Stoyan, Dressel, Ralf, Rodriguez-Polo, Ignacio, Behr, Rüdiger
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694496/
https://ncbi.nlm.nih.gov/pubmed/33167468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112422
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