The ubiquitin ligase c-CBL is expressed in undifferentiated marmoset monkey pluripotent stem cells but is not a general stem cell marker

The protein c-CBL is a ubiquitin ligase. It catalyzes the last step of the transfer of ubiquitin to target proteins. Upon completion of polyubiquitination, the target proteins are degraded. Clinically, it is important that c-CBL is mutated in a subset of patients who develop myeloid malignancies, wh...

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Опубликовано в: :Primate Biol
Главные авторы: Rodriguez-Polo, Ignacio, Nielsen, Maike, Debowski, Katharina, Behr, Rüdiger
Формат: Artigo
Язык:Inglês
Опубликовано: Copernicus GmbH 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041541/
https://ncbi.nlm.nih.gov/pubmed/32110709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5194/pb-4-231-2017
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