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IRF-1 expressed in the inner cell mass of the porcine early blastocyst enhances the pluripotency of induced pluripotent stem cells

BACKGROUND: Despite years of research, porcine-induced pluripotent stem cells (piPSCs) with germline chimeric capacity have not been established. Furthermore, the key transcription factors (TFs) defining the naïve state in piPSCs also remain elusive, even though TFs in the inner cell mass (ICM) are...

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Publicado en:Stem Cell Res Ther
Autores principales: Shi, Bingbo, Gao, Dengfeng, Zhong, Liang, Zhi, Minglei, Weng, Xiaogang, Xu, Junjun, Li, Junhong, Du, Xuguang, Xin, Yanli, Gao, Jie, Zhu, Qianqian, Cao, Suying, Liu, Zhonghua, Han, Jianyong
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694439/
https://ncbi.nlm.nih.gov/pubmed/33246502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01983-2
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