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Results and Clinical Interpretation of Germline RET Analysis in a Series of Patients with Medullary Thyroid Carcinoma: The Challenge of the Variants of Uncertain Significance

SIMPLE SUMMARY: About 25% of Thyroid Carcinomas of Medullary type occur in carriers of hereditary alterations in the RET gene. Different alterations are associated with different risks (highest, high, and moderate) and management depends on risk category. We explored prevalence, clinical presentatio...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Innella, Giovanni, Rossi, Cesare, Romagnoli, Maria, Repaci, Andrea, Bianchi, Davide, Cantarini, Maria Elena, Martorana, Davide, Godino, Lea, Pession, Andrea, Percesepe, Antonio, Pagotto, Uberto, Turchetti, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694403/
https://ncbi.nlm.nih.gov/pubmed/33167350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113268
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