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Development of a Sildenafil Citrate Microemulsion-Loaded Hydrogel as a Potential System for Drug Delivery to the Penis and Its Cellular Metabolic Mechanism

Sildenafil citrate is used to treat mild to moderate erectile dysfunction and premature ejaculation. However, it has low oral bioavailability, numerous adverse effects, and delayed onset of action. These problems may be resolved by transdermal delivery to the penis. Hence, sildenafil citrate was for...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Atipairin, Apichart, Chunhachaichana, Charisopon, Nakpheng, Titpawan, Changsan, Narumon, Srichana, Teerapol, Sawatdee, Somchai
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694282/
https://ncbi.nlm.nih.gov/pubmed/33158184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12111055
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