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Development of a Sildenafil Citrate Microemulsion-Loaded Hydrogel as a Potential System for Drug Delivery to the Penis and Its Cellular Metabolic Mechanism

Sildenafil citrate is used to treat mild to moderate erectile dysfunction and premature ejaculation. However, it has low oral bioavailability, numerous adverse effects, and delayed onset of action. These problems may be resolved by transdermal delivery to the penis. Hence, sildenafil citrate was for...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Atipairin, Apichart, Chunhachaichana, Charisopon, Nakpheng, Titpawan, Changsan, Narumon, Srichana, Teerapol, Sawatdee, Somchai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694282/
https://ncbi.nlm.nih.gov/pubmed/33158184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12111055
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