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Poziotinib Inhibits the Efflux Activity of the ABCB1 and ABCG2 Transporters and the Expression of the ABCG2 Transporter Protein in Multidrug Resistant Colon Cancer Cells

SIMPLE SUMMARY: Globally, colorectal cancer (CRC) is a leading cause of cancer deaths and chemotherapy, in combination with radiotherapy when appropriate, is used to treat the majority of CRC patients. However, the acquisition or development of drug resistance can decrease, or even abolish, the effi...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Zhang, Yongchao, Wu, Zhuo-Xun, Yang, Yuqi, Wang, Jing-Quan, Li, Jun, Sun, Zoey, Teng, Qiu-Xu, Ashby, Charles R., Yang, Dong-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694178/
https://ncbi.nlm.nih.gov/pubmed/33158067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113249
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