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Poziotinib Inhibits the Efflux Activity of the ABCB1 and ABCG2 Transporters and the Expression of the ABCG2 Transporter Protein in Multidrug Resistant Colon Cancer Cells

SIMPLE SUMMARY: Globally, colorectal cancer (CRC) is a leading cause of cancer deaths and chemotherapy, in combination with radiotherapy when appropriate, is used to treat the majority of CRC patients. However, the acquisition or development of drug resistance can decrease, or even abolish, the effi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Zhang, Yongchao, Wu, Zhuo-Xun, Yang, Yuqi, Wang, Jing-Quan, Li, Jun, Sun, Zoey, Teng, Qiu-Xu, Ashby, Charles R., Yang, Dong-Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694178/
https://ncbi.nlm.nih.gov/pubmed/33158067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113249
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