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Effects of Netarsudil on Actin-Driven Cellular Functions in Normal and Glaucomatous Trabecular Meshwork Cells: A Live Imaging Study

The actin cytoskeleton of trabecular meshwork (TM) cells is a therapeutic target for lowering intraocular pressure (IOP) in glaucoma patients. Netarsudil (the active ingredient in Rhopressa(TM)) is a Rho-associated protein kinase inhibitor that induces disassembly of actin stress fibers. Here, we us...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Keller, Kate E., Kopczynski, Casey
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693753/
https://ncbi.nlm.nih.gov/pubmed/33142742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9113524
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