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Targeting CREB in Cancer Therapy: A Key Candidate or One of Many? An Update

SIMPLE SUMMARY: Only 5% of all drug-related targets currently move from preclinical to clinical in cancer, and just some of them achieve patient’s bedside. Among others, intratumor heterogeneity and preclinical cancer model limitations actually represent the main reasons for this failure. Cyclic-AMP...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Sapio, Luigi, Salzillo, Alessia, Ragone, Angela, Illiano, Michela, Spina, Annamaria, Naviglio, Silvio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693618/
https://ncbi.nlm.nih.gov/pubmed/33126560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113166
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