ROS Overproduction Sensitises Myeloma Cells to Bortezomib-Induced Apoptosis and Alleviates Tumour Microenvironment-Mediated Cell Resistance

Multiple myeloma (MM) is a plasma cell neoplasm that remains incurable due to innate or acquired resistance. Although MM cells produce high intracellular levels of reactive oxygen species (ROS), we hypothesised that they could remain sensitive to ROS unbalance. We tested if the inhibition of ROS, on...

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Detaylı Bibliyografya
Yayımlandı:Cells
Asıl Yazarlar: Caillot, Mélody, Zylbersztejn, Florence, Maitre, Elsa, Bourgeais, Jérôme, Hérault, Olivier, Sola, Brigitte
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693395/
https://ncbi.nlm.nih.gov/pubmed/33114738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112357
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