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ROS Overproduction Sensitises Myeloma Cells to Bortezomib-Induced Apoptosis and Alleviates Tumour Microenvironment-Mediated Cell Resistance

Multiple myeloma (MM) is a plasma cell neoplasm that remains incurable due to innate or acquired resistance. Although MM cells produce high intracellular levels of reactive oxygen species (ROS), we hypothesised that they could remain sensitive to ROS unbalance. We tested if the inhibition of ROS, on...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Caillot, Mélody, Zylbersztejn, Florence, Maitre, Elsa, Bourgeais, Jérôme, Hérault, Olivier, Sola, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693395/
https://ncbi.nlm.nih.gov/pubmed/33114738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112357
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