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Mirtazapine exerts astrocyte-mediated dopaminergic neuroprotection

Mirtazapine, a noradrenergic and specific serotonergic antidepressant (NaSSA), is known to activate serotonin (5-HT) 1A receptor. Our recent study demonstrated that stimulation of astrocytic 5-HT1A receptors promoted astrocyte proliferation and upregulated antioxidative property in astrocytes to pro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kikuoka, Ryo, Miyazaki, Ikuko, Kubota, Natsuki, Maeda, Megumi, Kagawa, Daiki, Moriyama, Masaaki, Sato, Asuka, Murakami, Shinki, Kitamura, Yoshihisa, Sendo, Toshiaki, Asanuma, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693322/
https://ncbi.nlm.nih.gov/pubmed/33244123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77652-4
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