Distinct features of calcium handling and β‐adrenergic sensitivity in heart failure with preserved versus reduced ejection fraction

KEY POINTS: Heart failure (HF), the leading cause of death in developed countries, occurs in the setting of reduced (HFrEF) or preserved (HFpEF) ejection fraction. Unlike HFrEF, there are no effective treatments for HFpEF, which accounts for ∼50% of heart failure. Abnormal intracellular calcium dyna...

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Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Kilfoil, Peter J., Lotteau, Sabine, Zhang, Rui, Yue, Xin, Aynaszyan, Stephan, Solymani, Ryan E., Cingolani, Eugenio, Marbán, Eduardo, Goldhaber, Joshua I.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Cardiovascular
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693093/
https://ncbi.nlm.nih.gov/pubmed/32829489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP280425
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