Distinct features of calcium handling and β‐adrenergic sensitivity in heart failure with preserved versus reduced ejection fraction

KEY POINTS: Heart failure (HF), the leading cause of death in developed countries, occurs in the setting of reduced (HFrEF) or preserved (HFpEF) ejection fraction. Unlike HFrEF, there are no effective treatments for HFpEF, which accounts for ∼50% of heart failure. Abnormal intracellular calcium dyna...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Kilfoil, Peter J., Lotteau, Sabine, Zhang, Rui, Yue, Xin, Aynaszyan, Stephan, Solymani, Ryan E., Cingolani, Eugenio, Marbán, Eduardo, Goldhaber, Joshua I.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693093/
https://ncbi.nlm.nih.gov/pubmed/32829489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP280425
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